POLYNUCLEOTIDES
Under-eye rejuvenation, dark circles & full-face skin repair
Polynucleotides are regenerative injectable treatments made from highly purified DNA fragments. Rather than adding volume, they work by supporting cellular repair, fibroblast activity, hydration and the skin’s natural regenerative processes.
They are used to improve concerns such as fine lines, reduced elasticity, dull or tired-looking skin, dehydration and compromised skin quality, with results developing gradually as the tissue responds.

Expected Results
Downtime
Longevity
Improved skin repair, firmness and overall skin quality.
Mild redness, swelling or small bumps for 24–48 hours.
Results typically last 6–12 months with maintenance.
At a Glance

How does it work?
Cellular signalling
Polynucleotides are highly purified DNA fragments that act as biostimulatory signals within the skin, supporting cellular repair and regeneration.
Fibroblast activation
They help stimulate fibroblasts — the cells responsible for producing collagen, elastin and other components of the extracellular matrix — supporting improved firmness, elasticity and overall skin quality.
Tissue repair & microcirculation
Polynucleotides are associated with regenerative processes that may support tissue repair and local microcirculation, helping create a healthier environment within the skin.
Hydration & protection
They have water-binding properties that support hydration within the tissue and may also help reduce oxidative stress and inflammatory activity, contributing to improved skin resilience and recovery.
BOOK POLYNUCLEOTIDES
1 hr
From 350 British pounds
Interest-free instalments on treatments from £300 · No credit check
FAQ
Your questions, answered
Understanding treatment options and expected outcomes.
What are polynucleotides? Polynucleotides are regenerative injectable treatments that help repair damaged skin, stimulate collagen production and improve skin quality. They work by supporting the skin's natural healing and regeneration processes.
What do polynucleotides treat? Polynucleotides can help improve fine lines, skin laxity, dull skin, under-eye concerns, acne scars and overall skin texture while promoting healthier-looking skin.
How many polynucleotide treatments will I need? Most patients benefit from a course of 3 treatments, spaced approximately 2–4 weeks apart. Maintenance treatments are usually recommended every 6–12 months.
When will I see results from polynucleotides? Some improvements may be visible within a few weeks, with optimal results developing over the following months as collagen production increases.
Is there any downtime after polynucleotide treatment? Downtime is minimal. Mild redness, swelling or small injection bumps may occur and usually settle within 24–48 hours.
Can polynucleotides be combined with other treatments? Yes. Polynucleotides are often combined with treatments such as microneedling, skin boosters, anti-wrinkle injections or PRP, depending on your skin concerns and treatment goals.
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